NEXUS Ulcerative Colitis Research Study

Clinical Trial

Consider the NEXUS research study as the next step

Researchers are testing the safety, tolerability, and how the body responds to a study medication developed for the possible treatment of ulcerative colitis.

You may qualify to take part in this study if you are 18-75 years old, and:

Have been diagnosed with ulcerative colitis at least 3 months ago
Your ulcerative colitis is moderate to severe
Treatment for your ulcerative colitis has not been effective
You do not have Crohn's disease There are additional requirements to take part in this study.
The study doctor will discuss them with you.

If you qualify for this study, you will participate for up to 60 weeks (a year and 2 months).

The study medication and study-related tests are provided at no cost.

How It Works

About Clinical Trials

Clinical trials are medical research studies performed on people to determine whether new medical approaches, treatments, therapies, or devices are safe and effective. Doctors use clinical trials to learn how diseases start and progress, find new ways to improve health care, develop new therapies and preventive measures, and monitor changes in treatments over time. Clinical trials are the stepping-stones to bringing a drug or other therapy to market. Clinical trials demonstrate that a new drug is safe for people to utilize.

Why Participate?

Common reasons to participate in a clinical trial include:

All other treatment options have failed, and no further treatment options are readily available.
To obtain access to advanced treatments and protocols for their disease before the protocol becomes available to the general public.
To help researchers learn more about the impact of the trial protocol to benefit others.
To obtain access to medications and treatments required for their condition, at no cost throughout the trial.

More Information

Frequently Asked Questions

Is there a cost to be in this study?

The study medication and study-related tests are provided at no cost. You may also receive reimbursement for study-related travel expenses.

What will happen in the NEXUS study?

Researches are testing the safety, tolerability, and how the body responds to a study medication that is being developed for the possible treatment of UC. The study medication will be compared to a placebo. The placebo looks like the study medication, but it has no active ingredients.

What tests will take place?

Physical exams, vital signs (blood pressure, heart rate, temperature, blood draws, stool samples, endoscopies (colonoscopy or flexible sigmoidoscopy).

Am I eligible to take part?

You may qualify to take part in this study if you are 18 to 75 years old, and:

Have been diagnosed with UC at least three months ago
Your UC is moderate to severe
Treatment for your UC has not been effective
You do not have Chron's disease

Is your ulcerative colitis treatment not working?